The Translational Physiologist in Strengthening Research to Enhance Quality of Life
DOI :
https://doi.org/10.54548/njps.v39i2.1Résumé
Thematic Lecture presented to the Physiological Society of Nigeria at its 41st Annual Scientific Meeting held at the Rivers State University, Port-Harcourt, Rivers State from February 11 - 17, 2024
Téléchargements
Références
Akindele A. J., Fatokun A. A., Uzochukwu I. C., Steenkamp V., Agyare C., Familoni O. and James M. O. (2022). Editorial: Translational Research and Drug Repurposing for Non-Communicable Diseases (NCDs). Front. Pharmacol., Sec. Translational Pharmacology. 13; 202.
Cripe, T.P., Thomson B., Boat T.F. and Williams D.A. (2005). Promoting translational research in academic health centers: navigating the “roadmap.” Acad. Med. 80:1012-1018.
Curry SH (2008). Translational science: past, present, and future. BioTechniques for Preclinical Development. 44(2); i-viii.
Damba F.U., Mtshali N.G. and Chimbari M.J. (2022). Barriers and facilitators of translating health research findings into policy in sub-Saharan Africa: A Scoping Review. Humanities Soc. Sci. Coms. 9:65.
Farrell A.T., Panepinto P., Desai A.A., Kassim A.A., Lebensburger J., Walters M.C. et al. (2019). End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Advances. 3(23): 4002-4020.
Gilliland C. T., White J., Gee B., Kreeftmeijer-Vegter R., Bietrix F., Ussi A. E. et. al. (2019). The Fundamental Characteristics of a Translational Scientist. ACS Pharmacol. Transl. Sci., 2: 213−216.
Hall JE (2002). The promise of translational physiology. Am. J. Physiol. (Lung Cell Mol Physiol.) 283: L235–L236.
Homer-Vanniasinkam S. and Janice Tsui J. (2012). The continuing challenges of translational research: clinician-scientists' perspective. Cardiol. Res. Pract. 2012: 246710.
Jaja S.I., Ogungbemi S.O., Kehinde M.O. and Anigbogu C.N. (2016). Supplementation with l-arginine stabilizes plasma arginine and nitric oxide metabolites, suppresses elevated liver enzymes and peroxidation in sickle cell anaemia. Pathophysiol. 23: 81–85.
Jaja S.I., Oludemi B. F. and Renner J. K. (2002). The effect of load-bearing either on the back or on the chest on oxygen consumption and energy expenditure. Niger J. Health and Biomedical Sci. 1(1): 41-44.
Liebman M.N. and Marincola F.M. (2012). Expanding the perspective of translational medicine: the value of observational data. J.Translational Med. 10:61.
Marincola FM. (2003). Translational Medicine: A two-way road. J. Translational Med. Medicine 1(1):1-2.
Olatunji G., Emmanuel K., Osaghae O.W., Timilehin I., Aderinto N., Abdulbasit M.O. (2023). Enhancing clinical and translational research in Africa: a comprehensive exploration of challenges and opportunities for advancement. J. Clin. Translational Res. 9(5): 357-368
Piel F.B., Patil A.P., Howes R.E., Nyangiri O.A., Gething P.E., Dewi M., et al. (2013). Global epidemiology of sickle haemoglobin in neonates: a contemporary geosttistical model-based map and population estimates. Lancet 381:142–151.
Sadeghi A., Taherifard E., Ebrahimi N.D., Rafiei E., Hadianfard F. and Taherifard E (2023). Effects of L‐arginine supplementation in patients with sickle cell disease: A systematic review and meta‐analysis of clinical trials. Health Sci. Rep. 6: e1167.
Saka W.A., Anigbogu C.N., Kehinde M.O. and Jaja S.I. (2023). L-Arginine supplementation enhanced expression of glucose transporter (GLUT 1) in sickle cell anaemia subjects in the steady state. Cur. Res. Physiol. 6: 100096.
Salami A., Kanmod K.K. (2021). Translational medical research in Nigeria: challenges, prospects and recommendations for the future. Euro. J. Translational Clin. Med. 4(1):71-78.
Salisu, T. F., Okpuzor, J. E. and Jaja, S. I. (2019). Identification, characterization and quantification of chemical compounds in selected edible wild leafy vegetables. Ife J. Sci. 21(1): 215–227.
Salisu T.F., Ottu B.O., Oloyo A.K., Okpuzor J.E. and Jaja S.I. (2022). Assessment of wild African vegetables on cardiac functions, antioxidants and blood lipid profile in a rat model of myocardial infarction. FUW Trends in Sci. & Tech. J. 7(1): 070–082.
Seals DR (2013). Translational physiology: from molecules to public health. J. Physiol. 591: 3457–3469.
Tchernia D. and Diallo G. (2002). Sickle cell disease in Africa. Cur. Opinion in Hematol. 9(2):111-116.
van der Laan A.L. and Boenink M. (2012). Beyond Bench and Bedside: Disentangling the Concept of Translational Research. Health Care Analysis 23; 32-49.
Téléchargements
Publiée
Numéro
Rubrique
Licence
(c) Copyright Nigerian Journal of Physiological Sciences 2025
Ce travail est disponible sous la licence Creative Commons Attribution 4.0 International .
